BACKGROUND: The complex yet flexible cellular response to pathogens is orchestrated by the interaction of multiple signalling and metabolic pathways. The molecular regulation of this response has been studied in great detail but comprehensive and unambiguous diagrams describing these events are generally unavailable. Four key signalling cascades triggered early-on in the innate immune response are the toll-like receptor, interferon, NF-kappaB and apoptotic pathways, which co-operate to defend cells against a given pathogen. However, these pathways are commonly viewed as separate entities rather than an integrated network of molecular interactions. RESULTS: Here we describe the construction of a logically represented pathway diagram which attempts to integrate these four pathways central to innate immunity using a modified version of the Edinburgh Pathway Notation. The pathway map is available in a number of electronic formats and editing is supported by yEd graph editor software. CONCLUSION: The map presents a powerful visual aid for interpreting the available pathway interaction knowledge and underscores the valuable contribution well constructed pathway diagrams make to communicating large amounts of molecular interaction data. Furthermore, we discuss issues with the limitations and scalability of pathways presented in this fashion, explore options for automated layout of large pathway networks and demonstrate how such maps can aid the interpretation of functional studies. Helikar Tomas thelika@unmc.edu University of Nebraska - Lincoln 2011-09-06T15:26:55Z 2016-01-22T07:08:46Z

<span style="font-size: small;">Fas ligand (TNF superfamily, member 6)</span><div><span style="font-size: small;">UniProt Accession ID:&nbsp;</span><a href="http://www.uniprot.org/uniprot/P48023" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P48023</a></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01562" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P01562</a><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01563" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P01563</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P32881" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P32881</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01570" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P01570</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01571" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P01571</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01568" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P01568</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P05014" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P05014</a></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

<font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Interferon, gamma [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">(human)]</span><br/></font><div><font face="Georgia" size="2">UniProt Accession ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01579" style="text-decoration: none; background-color: rgb(255, 255, 255);">P01579</a></font></div><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/3458" ref="ordinalpos=2&amp;ncbi_uid=3458&amp;link_uid=3458" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">IFNG</span></a></font></div><div><font size="2" face="Georgia">NCBI Gene ID: 3458</font></div>

2015-11-15T16:17:18Z

tumor necrosis factor (TNF superfamily, member 2)<div>UniProt Accession ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01375" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P01375</a></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01574" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P01574</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P35228">P35228</a>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Interferon gamma receptor&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">1</span><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;[</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);"><span class="highlight">Homo sapiens</span></em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font></div><font face="Georgia" size="2">UniProt ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P15260" style="text-decoration: none; background-color: rgb(255, 255, 255);">P15260</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/3459" ref="ordinalpos=2&amp;ncbi_uid=3459&amp;link_uid=3459" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);">IFNGR1</a></font></div><div><font face="Georgia" size="2">NCBI Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 16.19982147216797px;">3459</span></font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P02545" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P02545</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q15750">Q15750</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P25963&nbsp;<div>Uniprot ID: Q04206&nbsp;</div><div>Uniprot ID: P19838</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P42575

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q14653" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q14653</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q00653

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O15455&nbsp;<div>Uniprot ID: Q8IUC6&nbsp;</div><div>Uniprot ID: Q86XR7</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P42224&nbsp;<div>Uniprot ID: P52630</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O60603<div>Uniprot ID: Q9Y2C9</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O15455&nbsp;<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q8IUC6&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q86XR7&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9UHD2</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9UHD2">Q9UHD2</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P25942<div>Uniprot ID: P29965</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P17181" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P17181</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9UER7" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q9UER7</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q03518">Q03518</a>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Apoptotic peptidase activating factor 1 [</span><em style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O14727" style="text-decoration: none; background-color: rgb(255, 255, 255);">O14727</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/317" ref="ordinalpos=1&amp;ncbi_uid=317&amp;link_uid=317" style="line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">APAF1</span></a></font></div><div><font face="Georgia" size="2">NCBI Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 17.999801635742188px;">317</span></font></div>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Toll interacting protein [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9H0E2" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q9H0E2</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/54472" ref="ordinalpos=1&amp;ncbi_uid=54472&amp;link_uid=54472" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">TOLLIP</span></a></font></div><div><font face="Georgia" size="2">Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 16.19982147216797px;">54472</span></font></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q92793" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q92793</a>

2015-11-15T16:17:18Z

<div><span style="line-height: 16px; background-color: rgb(255, 255, 255);"><font face="Georgia" size="2">Bcl2 antagonist of cell death</font></span></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q92934" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q92934</a></font><div><font face="Georgia" size="2">Gene Name: BAD</font></div><div><font face="Georgia" size="2">Gene ID: 572</font></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q15750&nbsp;<div>Uniprot ID: Q9NYJ8&nbsp;</div><div>Uniprot ID: O43318</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O14920

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q12933" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q12933</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q9UNN5

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q9NYK1

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q8IUC6">Q8IUC6</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q13568

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q9NYK1&nbsp;<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q99836&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P51617</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9NWZ3&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9Y4K3</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot iD:&nbsp;<a href="http://www.uniprot.org/uniprot/O15519" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O15519</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q14164&nbsp;<div>Uniprot ID: Q9UHD2</div>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span class="highlight" style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Caspase</span><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">8</span><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">, apoptosis-related cysteine peptidase [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;Q14790</font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/841" ref="ordinalpos=1&amp;ncbi_uid=841&amp;link_uid=841" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);">CASP8</a>&nbsp;</font></div><div><font face="Georgia" size="2">NCBI Gene ID: 841</font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P01574

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

<div><font face="Georgia" size="2">The protein kinase c family consists of 15 isozymes in humans [49].&nbsp;</font></div><div><font face="Georgia" size="2"><br/></font></div><div><font face="Georgia" size="2">Protein Kinase C alpha</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P17252">P17252</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCA</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5578</span></font></div><div><div><font face="Georgia" size="2">Protein Kinase C beta</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P05771" style="text-decoration: none; background-color: rgb(255, 255, 255);">P05771</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCB</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5579</span></font></div></div><div><div><div><font face="Georgia" size="2">Protein Kinase C gamma</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P05129" style="text-decoration: none; background-color: rgb(255, 255, 255);">P05129</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCG</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5582</span></font></div></div><div><div><font face="Georgia" size="2">Protein Kinase C delta</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q05655" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q05655</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCD</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5580</span></font></div></div><div><div><font face="Georgia" size="2">Protein Kinase C epsilon</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q02156" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q02156</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCE</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5581</span></font></div></div><div><div><font face="Georgia" size="2">Protein Kinase C eta</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P24723" style="text-decoration: none; background-color: rgb(255, 255, 255);">P24723</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCH</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5583</span></font></div></div><div><div><font face="Georgia" size="2">Protein Kinase C theta</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q04759" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q04759</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCQ</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5588</span></font></div></div><div><div><font face="Georgia" size="2">Protein Kinase C iota</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P41743" style="text-decoration: none; background-color: rgb(255, 255, 255);">P41743</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCI</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5584</span></font></div></div><div><div><font face="Georgia" size="2">Protein Kinase C zeta</font></div><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q05513">Q05513</a></font></div><div><font face="Georgia" size="2">Gene Name: PRKCZ</font></div><div><font face="Georgia" size="2">Gene ID:<span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">5590</span></font></div></div></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q16548

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O00463" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O00463</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P48023&nbsp;<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P25445&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q13158&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9UNN5&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span><span style="font-size: 10pt;">Q9UER7&nbsp;</span></div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span><span style="font-size: 10pt;">O15519</span></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q14653&nbsp;<div>Uniprot ID: Q92985&nbsp;</div>

2015-11-15T16:17:18Z

<div><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);"><font face="Georgia" size="2">Suppressor of cytokine signaling 3</font></span></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O14543">O14543</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/9021" ref="ordinalpos=1&amp;ncbi_uid=9021&amp;link_uid=9021" style="line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">SOCS3</span></a></font></div><div><font face="Georgia" size="2">Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 17.999801635742188px;">9021</span></font></div>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O60674" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O60674</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O95429<div>Uniprot ID: P19438</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P01584" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P01584</a>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P04179">P04179</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q92985" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q92985</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P09914" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P09914</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P10914" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P10914</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O60602

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P52630">P52630</a>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Interleukin-1 receptor-associated kinase 4 [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9NWZ3" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q9NWZ3</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/51135" ref="ordinalpos=1&amp;ncbi_uid=51135&amp;link_uid=51135" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">IRAK4</span></a></font></div><div><font face="Georgia" size="2">Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 16.19982147216797px;">51135</span></font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q16611" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q16611</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P10914" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P10914</a>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span class="highlight" style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Janus</span><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">&nbsp;</span><span class="highlight" style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">kinase</span><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">&nbsp;</span><span class="highlight" style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">1</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P23458" style="text-decoration: none; background-color: rgb(255, 255, 255);">P23458</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/3716" ref="ordinalpos=2&amp;ncbi_uid=3716&amp;link_uid=3716" style="line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);">JAK1</a></font></div><div><font face="Georgia" size="2">Gene ID: 3716</font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q53GL7">Q53GL7</a><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q2NL67" style="font-size: 10pt;">Q2NL67</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q8N3A8" style="font-size: 10pt;">Q8N3A8</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P09874" style="font-size: 10pt;">P09874</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9UKK3" style="font-size: 10pt;">Q9UKK3</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q8N5Y8" style="font-size: 10pt;">Q8N5Y8</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q7Z3E1" style="font-size: 10pt;">Q7Z3E1</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q8IXQ6" style="font-size: 10pt;">Q8IXQ6</a></div><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9H0J9" style="font-size: 10pt;">Q9H0J9</a></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q14249

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P14316" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P14316</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">TNF receptor-associated factor 6, E3 ubiquitin protein ligase [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font></div><font face="Georgia" size="2">Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9Y4K3" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q9Y4K3</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<span class="highlight" style="line-height: 17.999801635742188px; white-space: nowrap;"><a href="http://www.ncbi.nlm.nih.gov/gene/7189" ref="ordinalpos=1&amp;ncbi_uid=7189&amp;link_uid=7189" style="line-height: 17.999801635742188px; white-space: nowrap;">TRAF6</a></span></font></div><div><font face="Georgia" size="2">Gene ID: 7189</font></div>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q00978" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q00978</a>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">interferon gamma receptor&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">1</span><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;[</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);"><span class="highlight">Homo sapiens</span></em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P15260" style="text-decoration: none; background-color: rgb(255, 255, 255);">P15260</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/3459" ref="ordinalpos=2&amp;ncbi_uid=3459&amp;link_uid=3459" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);">IFNGR1</a></font></div><div><font face="Georgia" size="2">NCBI Gene ID: 3459</font></div><div><font face="Georgia" size="2"><br/></font></div><div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Interferon gamma receptor</span><span class="highlight" style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">2</span><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(interferon gamma transducer 1) [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);"><span class="highlight">Homo sapiens</span></em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span><br/></font><div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P38484" style="text-decoration: none; background-color: rgb(255, 255, 255);">P38484</a></font></div></div><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/3460" ref="ordinalpos=9&amp;ncbi_uid=3460&amp;link_uid=3460" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);">IFNGR2</a></font></div><div><font face="Georgia" size="2">NCBI Gene ID: 3460</font></div>

2015-11-15T16:17:18Z

<font face="Georgia"><span style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">TNFRSF1A-associated via death domain [</span><em style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span><br/></font><div><font face="Georgia"><font size="2">UniProt Accession ID:&nbsp;</font><a href="http://www.uniprot.org/uniprot/Q15628" style="font-size: small; text-decoration: none; background-color: rgb(255, 255, 255);">Q15628</a></font></div><div><font face="Georgia">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/8717" ref="ordinalpos=1&amp;ncbi_uid=8717&amp;link_uid=8717" style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">TRADD</span></a></font></div><div><font face="Georgia">NCBI Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); font-size: 12.222222328186035px; line-height: 17.999801635742188px;">8717</span></font></div>

2015-11-15T16:17:18Z

<table border="0" cellpadding="0" cellspacing="0" width="964" style="border-collapse:\r\n collapse;width:723pt"><tbody><tr height="20" style="height:15.0pt">\r\n <td height="20" class="xl65" width="964" style="height:15.0pt;width:723pt">Deoxyribonucleic\r\n acid</td></tr></tbody></table>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P40933

2015-11-15T16:17:18Z

<font face="Arial, Verdana" size="2">Uniprot ID: Q95ND5</font>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q00653&nbsp;<div>Uniprot ID: Q01201</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P46695" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P46695</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Fas (TNFRSF6)-associated via death domain [</span><em style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;Q13158</font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/8772" ref="ordinalpos=1&amp;ncbi_uid=8772&amp;link_uid=8772" style="line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">FADD</span></a></font></div><div><font face="Georgia" size="2">NCBI Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 17.999801635742188px;">8772</span></font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13490" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q13490</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P29460

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q07817&nbsp;

2015-11-15T16:17:18Z

Unipro<span style="font-size: 10pt;">t ID:&nbsp;</span><a href="http://www.uniprot.org/uniprot/Q9NYJ8" style="font-size: 10pt;">Q9NYJ8</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q16548" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q16548</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O60602">O60602</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P03269">P03269</a>

2015-11-15T16:17:18Z

<div style="font-family: Arial, Verdana; font-size: 10pt; font-style: normal; font-variant: normal; font-weight: normal; line-height: normal;">Fas (TNF receptor superfamily, member&nbsp;<span style="font-size: 10pt;">6)</span></div><div><span style="font-family: Arial, Verdana; font-size: 10pt; font-style: normal; font-variant: normal; font-weight: normal; line-height: normal;">Uniprot ID:&nbsp;</span><font face="Arial, Verdana" size="2">P25445</font></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

<div><span style="font-size: 10pt;">Uniprot ID:&nbsp;Q9NYK1&nbsp;</span></div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q99836&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P51617&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9NWZ3</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q00653&nbsp;<div>Uniprot ID: Q01201</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q99558">Q99558</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q07817<div>Uniprot ID: Q92934</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9BXH1" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q9BXH1</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q9Y275&nbsp;<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q02223&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:</span>&nbsp;O00463</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

<div><font face="Georgia"><span style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Activating transcription factor 2 [</span><em style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">(human)]</span></font></div><div><font face="Georgia">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P15336" style="font-size: small; text-decoration: none; background-color: rgb(255, 255, 255);">P15336</a></font></div><div><font face="Georgia">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/1386" ref="ordinalpos=1&amp;ncbi_uid=1386&amp;link_uid=1386" style="font-size: 13.333333969116211px; line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">ATF2</span></a></font></div><div><font face="Georgia">NCBI Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); font-size: 12.222222328186035px; line-height: 17.999801635742188px;">1386</span></font></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P02778" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P02778</a>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q01201">Q01201</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q14249

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q09472

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P14778" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P14778</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P20749" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P20749</a>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O60603">O60603</a>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9Y572">Q9Y572</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q13568

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P25445

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P51617" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P51617</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q02556" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q02556</a>

2015-11-15T16:17:18Z

<font face="Arial, Verdana" size="2">Uniprot ID: Q9NYK1<br/></font><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><font face="Arial, Verdana" size="2">&nbsp;Q99836 &nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">Q9Y4K3&nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">Q13568</font></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Represents the cell event: apoptosis [1, 2].&nbsp;

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O00273" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O00273</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

<font face="Arial, Verdana" size="2">B-Cell CLL/lymphoma 2</font><div><font face="Arial, Verdana" size="2"><br/></font></div><div><font face="Arial, Verdana" size="2">UniProt ID:&nbsp;</font><a href="http://www.uniprot.org/uniprot/P10415" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P10415</a></div><div>Gene Name: BCL2</div><div>Gene ID: 596</div>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Myeloid differentiation primary response 88 [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q99836">Q99836</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/4615" ref="ordinalpos=1&amp;ncbi_uid=4615&amp;link_uid=4615" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">MYD88</span></a></font></div><div><font face="Georgia" size="2">Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 16.19982147216797px;">4615</span></font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P00973">P00973</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P19525

2015-11-15T16:17:18Z

<span style="line-height: 16px; background-color: rgb(255, 255, 255);"><font face="Georgia" size="2">Signal transducer and activator of transcription 1</font></span><div><font face="Georgia" size="2"><span style="line-height: 15.989583969116211px;">Uniport ID:&nbsp;</span><a href="http://www.uniprot.org/uniprot/P42224">P42224</a><span style="line-height: 15.989583969116211px;"><br/></span></font><div><div style="line-height: normal;"><span style="line-height: 16px; background-color: rgb(255, 255, 255);"><font face="Georgia" size="2">Gene Name: STAT1&nbsp;</font></span></div></div></div><div style="line-height: normal;"><font face="Georgia" size="2"><span style="line-height: 16px; background-color: rgb(255, 255, 255);">Gene ID:&nbsp;</span><span style="background-color: rgb(255, 255, 255); line-height: 16.78819465637207px; white-space: nowrap;">6772</span></font></div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q13568&nbsp;<div>Uniprot ID: Q92985&nbsp;</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O15455<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q8IUC6&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q86XR7&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:</span>&nbsp;Q13546</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P05198

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q15306" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q15306</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P62805" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P62805</a>

2015-11-15T16:17:18Z

<span style="color: rgb(64, 56, 56); font-family: 'Lucida Sans Unicode', Arial, 'Lucida Grande', Tahoma, Verdana, Helvetica, sans-serif; line-height: 19.200000762939453px; text-align: justify; background-color: rgb(255, 255, 255);">membrane-anchored scaffold protein for Csk</span>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q9NR28

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q16611

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13568" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q13568</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O60603&nbsp;<div>Uniprot ID: Q9Y2C9&nbsp;</div><div>Uniprot ID: Q9H0E2&nbsp;</div><div>Uniprot ID: Q99836&nbsp;</div><div>Uniprot ID: O43187&nbsp;</div><div>Uniprot ID: P51617&nbsp;</div><div>Uniprot ID: Q9NWZ3</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q92890

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q00978" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q00978</a>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Interleukin-1 receptor-associated kinase 2 [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O43187" style="text-decoration: none; background-color: rgb(255, 255, 255);">O43187</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/3656" ref="ordinalpos=1&amp;ncbi_uid=3656&amp;link_uid=3656" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">IRAK2</span></a></font></div><div><font face="Georgia" size="2">NCBI Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 16.19982147216797px;">3656</span></font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O15162">O15162</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O14625" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O14625</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q14653&nbsp;<div>Uniprot ID: Q92985&nbsp;</div>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P42224">P42224</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P19438" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P19438</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P19525

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9Y2C9">Q9Y2C9</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q14653" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q14653</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P05161

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O00220" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O00220</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P48551" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P48551</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O60602&nbsp;<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q99836&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>O43187&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P51617&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9NWZ3&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9Y4K3</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P04637" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P04637</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q14164" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q14164</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q00978" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q00978</a>

2015-11-15T16:17:18Z

Uniprot ID: Q00653

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P29466

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13489" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q13489</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O43464" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O43464</a>

2015-11-15T16:17:18Z

<font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Caspase 9, apoptosis-related cysteine peptidase [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font><div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">UniProt ID:&nbsp;</span><a href="http://www.uniprot.org/uniprot/P55211" style="text-decoration: none; background-color: rgb(255, 255, 255);">P55211</a></font></div><div><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Gene Name:&nbsp;</span><a href="http://www.ncbi.nlm.nih.gov/gene/842" ref="ordinalpos=1&amp;ncbi_uid=842&amp;link_uid=842" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">CASP9</span></a></font></div><div><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);"><font face="Georgia" size="2">Gene ID: 842</font></span></div>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O14763" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O14763</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O75569">O75569</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P20333" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P20333</a><div><br/></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P55210

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P25942&nbsp;<div>Uniprot ID: P29965&nbsp;</div><div>Uniprot ID: Q13114</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P08107" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P08107</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P98170" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P98170</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9NYK1">Q9NYK1</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q05513">Q05513</a>

2015-11-15T16:17:18Z

<div>Uniprot ID:&nbsp;Q14653&nbsp;</div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13568" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">Q13568</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P48023&nbsp;<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P25445&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q13158&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9UNN5&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9UER7</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q9Y275&nbsp;<div>Uniprot ID: Q02223</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13794">Q13794</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P09913" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P09913</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P48023&nbsp;<div>Uniprot ID: P25445</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q13568<div>Uniprot ID: Q92985&nbsp;</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q00653" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q00653</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P10415<div>Uniprot ID: Q07812</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O00206">O00206</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q86XR7">Q86XR7</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q12933" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q12933</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P17706">P17706</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O15111" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O15111</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P04637" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P04637</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P25963">P25963</a>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O95831">O95831</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q00653

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P04839" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P04839</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P10914" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P10914</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P13501" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P13501</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O43464" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O43464</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P33076" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P33076</a>

2015-11-15T16:17:18Z

<div><span style="font-size: 10pt;">Uniprot ID:&nbsp;Q9NR96&nbsp;</span></div><div><span style="font-size: 10pt;">Uniprot ID:</span>&nbsp;Q99836 &nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P51617&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9NWZ3&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9Y4K3</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P19525&nbsp;<div>Uniprot ID: Q4V8C7</div>

2015-11-15T16:17:18Z

<div><font face="Georgia" size="2"><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">BH3 interacting domain death agonist [</span><em style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font></div><div><font face="Georgia" size="2">UniProt Accession ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P55957" style="text-decoration: none; background-color: rgb(255, 255, 255);">P55957<br/></a><font>Gene Name:&nbsp;</font><a href="http://www.ncbi.nlm.nih.gov/gene/637" ref="ordinalpos=1&amp;ncbi_uid=637&amp;link_uid=637" style="color: rgb(100, 42, 143); line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">BID</span></a></font></div><div><font face="Georgia" size="2">Gene ID: 637</font></div>

2015-11-15T16:17:18Z

Uniport iD:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13077" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q13077</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P01574

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P17181" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P17181</a><div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P48551" style="font-size: small; text-decoration: none; font-family: sans-serif; background-color: rgb(255, 255, 255);">P48551</a></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P05362" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P05362</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13114" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q13114</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q07325" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q07325</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q14249

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID: Q07817&nbsp;

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q14185" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q14185</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P99999" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P99999</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P49662

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P17947">P17947</a>

2015-11-15T16:17:18Z

<div>\r\n \r\n \r\n \r\n <div class="page" title="Page 3">\r\n <div class="section">\r\n <div class="layoutArea">\r\n <div class="column">\r\n <p><font face="Georgia" size="2">BAX represents BAX (or BAK) activation by insertion into\r\nthe outer membrane of mitochondria and oligomerization [1].&nbsp;</font></p>\r\n </div>\r\n </div>\r\n </div>\r\n </div></div><div style="font-size: 10pt; font-family: Arial, Verdana;"><font face="Georgia" size="2"><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">BCL2-associated X protein [</span><em style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">Homo sapiens</em><span style="line-height: 17.999801635742188px; background-color: rgb(255, 255, 255);">&nbsp;(human)]</span></font></div><font face="Georgia" size="2" style="font-size: 10pt; font-family: Arial, Verdana;">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q07812" style="text-decoration: none; background-color: rgb(255, 255, 255);">Q07812</a></font><div style="font-size: 10pt; font-family: Arial, Verdana;"><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/581" ref="ordinalpos=1&amp;ncbi_uid=581&amp;link_uid=581" style="line-height: 17.999801635742188px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">BAX</span></a></font></div><div style="font-size: 10pt; font-family: Arial, Verdana;"><font face="Georgia" size="2">NCBI Gene ID: 581</font></div>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O75582">O75582</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O15455&nbsp;<div>Uniprot ID: Q8IUC6&nbsp;</div><div>Uniprot ID:&nbsp;Q86XR7&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q13546&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9Y572</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O15455

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P23497">P23497</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O00206<div>Uniprot ID: Q8IUC6&nbsp;</div><div>Uniprot ID: Q86XR7</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P19784" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P19784</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P58753">P58753</a>

2015-11-15T16:17:18Z

<div><span style="line-height: 19.999780654907227px; background-color: rgb(255, 255, 255);"><font face="Georgia" size="2">Suppressor of cytokine signaling 1</font></span></div><font face="Georgia" size="2">Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O15524">O15524</a></font><div><font face="Georgia" size="2">Gene Name:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/gene/8651" ref="ordinalpos=1&amp;ncbi_uid=8651&amp;link_uid=8651" style="line-height: 19.999780654907227px; white-space: nowrap; background-color: rgb(255, 255, 255);"><span class="highlight">SOCS1</span></a></font></div><div><font face="Georgia" size="2">Gene ID:&nbsp;<span style="background-color: rgb(255, 255, 255); line-height: 17.999801635742188px;">8651</span></font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P55212

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O95831">O95831</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O43903

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P28065">P28065</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P20749&nbsp;<div>Uniprot ID: 00653</div>

2015-11-15T16:17:18Z

Uniprot ID: P50591

2015-11-15T16:17:18Z

<font face="Arial, Verdana" size="2">Uniport ID: O14763</font>

2015-11-15T16:17:18Z

Unprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O95429" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">O95429</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O60602&nbsp;<div>Uniprot ID:&nbsp;Q99836&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>O43187&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P51617&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:</span>&nbsp;Q9NWZ3</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9NR96">Q9NR96</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O15455&nbsp;<br/><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q8IUC6&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:</span>&nbsp;Q86XR7&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9Y4K3</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P10914" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P10914</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P09912

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q00653&nbsp;<div>Uniprot ID: Q01201</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O95831&nbsp;<div>Uniprot ID: P08107</div>

2015-11-15T16:17:18Z

Represents the apoptosome, an multimeric protein complex that mediates the activation of apoptosis [1,2].&nbsp;

2015-11-15T16:17:18Z

<div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O43318" style="font-size: 10pt;">Q99759</a></div><div><br/></div>null<br/><br/>null<br/><br/>null

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;O14727&nbsp;<div>Uniprot ID: P99999</div>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13546">Q13546</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P29597" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P29597</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O15455">O15455</a>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O95831">O95831</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q9Y6K9" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q9Y6K9</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;Q92851

2015-11-15T16:17:18Z

<div>Uniprot ID:&nbsp;Q14653&nbsp;</div>Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13568" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q13568</a>

2015-11-15T16:17:18Z

<font face="Arial, Verdana" size="2">Uniprot ID: O60603&nbsp;</font><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:&nbsp;</span><font face="Arial, Verdana" size="2">Q9Y2C9&nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">Q9H0E2&nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">Q99836&nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">O43187&nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">P51617&nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">Q9NWZ3&nbsp;</font></div><div><span style="font-family: Arial, Verdana; font-size: small;">Uniprot ID:</span><span style="font-family: Arial, Verdana; font-size: small;">&nbsp;</span><font face="Arial, Verdana" size="2">Q9Y4K3</font></div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q02223" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q02223</a>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/P14316" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">P14316</a>

2015-11-15T16:17:18Z

<div><span style="font-size: 10pt;">Uniprot ID:&nbsp;Q9NR96&nbsp;</span></div><div>Uniprot ID:&nbsp;Q99836 &nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>P51617&nbsp;</div><div><span style="font-size: 10pt;">Uniprot ID:&nbsp;</span>Q9NWZ3</div>

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P32455

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q13546">Q13546</a>

2015-11-15T16:17:18Z

Unprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q14653" style="text-decoration: none; font-family: sans-serif; font-size: small; background-color: rgb(255, 255, 255);">Q14653</a>

2015-11-15T16:17:18Z
2015-11-15T16:17:18Z 2015-11-15T16:17:18Z

Uniprot ID:&nbsp;P48023

2015-11-15T16:17:18Z

Uniprot ID:&nbsp;<a href="http://www.uniprot.org/uniprot/Q00987">Q00987</a>

2015-11-15T16:17:18Z

Uniport ID:&nbsp;<a href="http://www.uniprot.org/uniprot/O75569">O75569</a>

2015-11-15T16:17:18Z
S_288 1 S_243 1 S_305 1 S_305 1 S_305 1 S_305 1 S_221 1 S_205 1 S_231 1 S_239 1 S_102 1 S_205 1 S_231 1 S_239 1 S_276 1 S_153 1 S_317 1 S_184 1 S_305 1 S_267 1 S_38 1 S_225 1 S_156 1 S_68 1 S_132 1 S_258 1 S_183 1 S_12 1 S_17 1 S_165 1 S_186 1 S_305 1 S_151 1 S_157 1 S_75 1 S_120 1 S_60 1 S_156 1 S_282 1 S_305 1 S_305 1 S_66 1 S_78 1 S_305 1 S_305 1 S_230 1 S_144 1 S_305 1 S_315 1 S_145 1 S_58 1 S_40 1 S_297 1 S_96 1 S_6 1 S_51 1 S_297 1 S_96 1 S_6 1 S_134 1 S_297 1 S_96 1 S_6 1 S_242 1 S_297 1 S_96 1 S_6 1 S_188 1 S_297 1 S_96 1 S_6 1 S_308 1 S_297 1 S_96 1 S_6 1 S_289 1 S_297 1 S_96 1 S_6 1 S_305 1 S_305 1 S_305 1 S_211 1 S_119 1 S_31 1 S_305 1 S_135 1 S_108 1 S_80 1 S_229 1 S_112 1 S_305 1 S_127 1 S_34 1 S_300 1 S_269 1 S_192 1 S_17 1 S_61 1 S_214 1 S_115 1 S_47 1 S_53 1 S_198 1 S_16 1 S_92 1 S_86 1 S_39 1 S_273 1 S_117 1 S_98 1 S_80 1 S_305 1 S_214 1 S_42 1 S_177 1 S_305 1 S_305 1 S_286 1 S_181 1 S_55 1 S_305 1 S_139 1 S_261 1 S_117 1 S_44 1 S_39 1 S_236 1 S_100 1 S_191 1 S_249 1 S_305 1 S_315 1 S_169 1 S_305 1 S_305 1 S_254 1 S_117 1 S_76 1 S_305 1 S_305 1 S_305 1 S_138 1 S_4 1 S_57 1 S_103 1 S_305 1 S_305 1 S_66 1 S_291 1 S_296 1 S_260 1 S_45 1 S_109 1 S_128 1 S_117 1 S_242 1 S_161 1 S_305 1 S_305 1 S_66 1 S_117 1 S_305 1 S_117 1 S_240 1 S_174 1 S_69 1 S_137 1 S_149 1 S_274 1 S_159 1 S_101 1 S_305 1 S_279 1 S_154 1 S_304 1 S_229 1 S_33 1 S_32 1 S_266 1 S_229 1 S_33 1 S_304 1 S_305 1 S_305 1 S_305 1 S_230 1 S_145 1 S_206 1 S_36 1 S_69 1 S_137 1 S_149 1 S_180 1 S_190 1 S_121 1 S_305 1 S_208 1 S_226 1 S_118 1 S_257 1 S_30 1 S_248 1 S_92 1 S_230 1 S_281 1 S_215 1 S_52 1 S_120 1 S_305 1 S_233 1 S_172 1 S_166 1 S_10 1 S_54 1 S_173 1 S_305 1 S_315 1 S_37 1 S_92 1 S_83 1 S_73 1 S_270 1 S_154 1 S_305 1 S_305 1 S_305 1 S_305 1 S_305 1 S_272 1 S_80 1 S_170 1 S_117 1 S_305 1 S_66 1 S_78 1 S_36 1 S_80 1 S_149 1 S_170 1 S_121 1 S_179 1 S_88 1 S_99 1 S_91 1 S_305 1 S_293 1 S_213 1 S_54 1 S_39 1 S_173 1 S_66 1 S_144 1 S_18 1 S_10 1 S_315 1 S_315 1 S_305 1 S_39 1 S_139 1 S_173 1 S_66 1 S_64 1 S_22 1 S_305 1 S_86 1 S_66 1 S_173 1 S_82 1 S_305 1 S_170 1 S_5 1 S_8 1 S_12 1 S_300 1 S_155 1 S_84 1 S_277 1 S_74 1 S_305 1 S_78 1 S_66 1 S_129 1 S_29 1 S_222 1 S_70 1 S_278 1 S_263 1 S_39 1 S_152 1 S_140 1 S_120 1 S_234 1 S_14 1 S_69 1 S_27 1 S_137 1 S_149 1 S_305 1 S_195 1 S_305 1 S_39 1 S_39 1 S_316 1 S_64 1 S_66 1 S_162 1 S_204 1 S_294 1 S_172 1 S_305 1 S_20 1 S_305 1 S_316 1 S_66 1 S_139 1 S_163 1 S_261 1 S_78 1 S_139 1 S_163 1 S_261 1 S_173 1 S_166 1 S_10 1 S_54 1 S_305 1 S_305 1 S_287 1 S_80 1 S_244 1 S_305 1 S_121 1 S_305 1 S_305 1 S_13 1 S_81 1 S_220 1 S_79 1 S_260 1 S_117 1 S_315 1 S_55 1 S_305 1 S_305 1 S_143 1 S_154 1 S_113 1 S_305 1 S_299 1 S_296 1 S_306 1 S_45 1 S_19 1 S_251 1 S_305 1 S_117 1 S_305 1 S_305 1 S_307 1 S_218 1 S_24 1 S_92 1 S_35 1 S_194 1 S_309 1 S_39 1 S_173 1 S_166 1 S_10 1 S_54 1 S_3 1 S_105 1 S_158 1 S_123 1 S_190 1 S_43 1 S_229 1 S_33 1 S_304 1 S_315 1 S_148 1 S_263 1 S_141 1 S_305 1 S_107 1 S_34 1 S_117 1 S_305 1 S_305 1 S_189 1 S_113 1 S_7 1 S_278 1 S_303 1 S_11 1 S_102 1 S_1 1 S_80 1 S_149 1 S_170 1 S_139 1 S_261 1 S_290 1 S_66 1 S_278 1 S_200 1 S_113 1 S_110 1 S_78 1 S_66 1 S_311 1 S_80 1 S_120 1 S_121 1 S_182 1 S_203 1 S_305 1 S_117 1 S_173 1 S_10 1 S_39 1 S_169 1 S_117 1 S_10 1 S_166 1 S_54 1 S_122 1 S_66 1 S_165 1 S_202 1 S_198 1 S_72 1 S_301 1 S_187 1 S_23 1 S_60 1 S_72 1 S_301 1 S_187 1 S_23 1 S_169 1 S_305 1 S_169 1 S_167 1 S_238 1 S_278 1 S_126 1 S_139 1 S_315 1 S_121 1 S_147 1 S_70 1 S_278 1 S_263 1 S_111 1 S_305 1 S_315 1 S_305 1 S_160 1 S_133 1 S_20 1 S_302 1 S_39 1 S_224 1 S_38 1 S_225 1 S_207 1 S_273 1 S_318 1 S_69 1 S_137 1 S_149 1 S_305 1 S_305 1 S_59 1 S_201 1 S_232 1 S_245 1 S_45 1 S_9 1 S_305 1 S_66 1 S_78 1 S_7 1 S_229 1 S_297 1 S_33 1 S_212 1 S_264 1 S_17 1 S_305 1 S_131 1 S_196 1 S_66 1 S_39 1 S_230 1 S_305 1 S_31 1 S_67 1 S_69 1 S_137 1 S_149 1 S_305 1 S_12 1 S_80 1 S_313 1 S_49 1 S_271 1 S_255 1 S_139 1 S_156 1 S_81 1 S_11 1 S_125 1 S_41 1 S_232 1 S_209 1 S_298 1 S_201 1 S_305 1 S_26 1 S_259 1 S_262 1 S_305 1 S_305 1 S_305 1 S_315 1 S_305 1 S_193 1 S_127 1 S_170 1 S_171 1 S_80 1 S_305 1 S_66 1 S_1 1 S_69 1 S_137 1 S_149 1 S_66 1 S_78 1 S_273 1 S_39 1 S_44 1 S_15 1 S_179 1 S_265 1 S_130 1 S_230 1 S_66 1 S_230 1 S_39 1